Hemodialysis and the intubated salicylate-toxic patient

May 20, 2017, 12:53 pm


The association of hemodialysis and survival in intubated salicylate-poisoned patients. McCabe DJ, Lu JJ. Am J Emerg Med 2017 Apr 10 [Epub ahead of print]


[Disclosure: the co-authors of this paper are members of the Toxikon Consortium in Chicago, as am I.]

This retrospective observational study looked at cases from the Illinois Poison Center over 12 years (2003 thru …

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Hemp seed oil may possibly (but not probably) cause cannabinoid poisoning

May 10, 2017, 1:41 am

hemp seed oil★★½☆☆

Cannabinoid Poisoning by Hemp Seed Oil in a Child. Chinello M et al. Pediatr Emerg Care 2017;33:344-345.


This interesting but non-dispositive short case report from Italy suggests that, in rare instances, commercially marketed hemp seed oil can cause mild cannabinoid toxicity. A 2-year-7-month old male was brought to hospital with altered mental status and several hours of “decreased alertness, …

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Tox Tunes #110: Nutmeg (John Legend & Stephen Colbert)

May 7, 2017, 1:38 pm

Started thinking about this song again earlier in the week as I prepared to take part in an hour-long discussion of the spice on Connecticut Public Radio’s Colin McEnroe Show. The discussion touched on many aspects the spice: historical, economic, culinary, medicinal, and toxicological.

To listen to the show, click here.

To read my 2011 Emergency Medicine News

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TPR Podcast Episode #14: VX and the Assassination of Kim Jong-Nam

March 30, 2017, 2:43 pm

When Kim Jong Nam — the half-brother of Korean leader Kim Jong Un — was assassinated in February while waiting for a flight at the Kuala Lumpur International Airport in Malaysia, attention was focused on one of the deadliest chemicals in the world: the nerge agent VX. What is VX, why is it such an effective poison, and how are victims of exposure managed medically. These are some of the questions we'll be examining in this edition of the TPR podcast.
Podcast Episode

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Tox Tunes #109: I Killed Robert Johnson (The Stone Foxes)

March 5, 2017, 10:20 pm

More myths and legends are attached to the life of Robert Johnson (1911 – 1938) than surround any other American blues artist. It’s said that he sold his soul to the devil down at a Mississippi crossroads in return for the ability to play guitar with a technique that musicians like Eric Clapton are still trying to replicate. It’s said …

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Labetalol in acute cocaine toxicity: is it safe?

March 1, 2017, 2:10 pm


Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol. Richards JR et al. J Emerg Med 2017 Mar;52:311-313.


There has long been a debate among toxicologists — still unresolved — as to whether it is safe to use a beta-blocker to treat cocaine-related hypertension and tachycardia. The (theoretical) concern is that since cocaine is both an α- and …

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Tox Tunes #108: Commit a Crime (Howlin’ Wolf)

February 26, 2017, 1:09 pm

You put poison in my coffee, instead of milk or cream
You put poison in my coffee, instead of milk or cream
You bout the evilest woman, that I ever seen

You mixed my drinks with a can of Red Devil lye
You mixed my drinks with a can of Red Devil lye
Then you sit down, watch me, hopin’

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Did the nerve agent VX kill Kim Jong Nam?

February 24, 2017, 2:44 pm

Last night Malaysian authorities announced that they identified the nerve agent VX taken off the face of Kim Jong Nam, who was murdered on February 13 at Kuala Lumpur International Airport.

As the History Channel video above indicates, nerve agents are potent acetylcholinesterase inhibitors that utilize the same mechanism as organophosphate insecticides such as parathion. Conceptually, the effect of VX …

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Must-watch: video showing murder of Kim Jong Nam

February 22, 2017, 1:25 pm

Screen Shot 2017-02-22 at 10.24.10 AM

Extraordinary security footage from Kuala Lumpur International Airport in Malaysia showing details surrounding the February 13 killing by poison of Kim Jong Nam, the half-brother of North Korea leader Kim Jong Un. The video was posted by Fuji Television and the Wall Street Journal, and can be seen by clicking here.

The video makes it possible to establish …

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