Death after consuming a marijuana edible

July 23, 2015, 6:08 pm

Screen Shot 2015-07-23 at 2.01.10 PM★★★★☆

Death Following Ingestion of an Edible Marijuana Product — Colorado, March 2014. MMWR 2015 July 24;64:771-772.

Full Text

This report describes the investigation by the Colorado Department of Public Health and Environment (CDPHE) into a well-publicized fatality that occurred shortly after recreational marijuana became available in that state.

In March 2014, a 19-year-old man ingested one piece of a marijuana …

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5F-ADB-PINACA and other extremely potent new synthetic cannabindoids

July 22, 2015, 5:18 pm

IndoleVSIndazole

★★★½☆

Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA. Banister SD et al. ACS Chem Neurosci 2015 July 17 [Epub ahead of print]

Abstract

As TPR noted in a recent post, many recently reported cases of severe toxicity or death associated with exposure to synthetic cannabinoids (SCs) involved relatively new …

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Serious toxicity and fatalities from synthetic cannabinoids

July 20, 2015, 1:44 pm

crazy.monkey-246x300★★★½☆

Synthetic Cannabinoid—Related Illnesses and Deaths. Trecki J et al. N Engl J Med 2015 Jul 9;373:103-107.

Reference

As the authors point out in this interesting article, there has been a recent surge in reports of fatalities and severe toxicity from synthetic cannabinoids (SCs). This is likely from a combination of increased incidence and more diligent surveillance.

The most interesting part …

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Tox Tunes #99: Casey Jones (Grateful Dead)

July 5, 2015, 2:49 pm

The critical response to the final 3 performances of the Grateful Dead’s “Fare Thee Well” tour has been decidedly mixed. In the New York Times, Jon Pareles reported that “Even with a handful of the Dead’s inevitable stumbles, the music was strong.”

On the other hand, Greg Kot’s review in the Chicago Tribune was headlined “Grateful Dead pay

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Tox Tunes #98: Truckin’ (The Grateful Dead)

July 3, 2015, 6:53 pm

Surprisingly, “Tox Tunes” has featured only one Grateful Dead song so far. This weekend seemed a good time to catch up, as the remnants of The Dead play their farewell concerts at Soldier Field in Chicago in the biggest festival the Windy City has seen since smaccUS.

There are, of course, a number of drug references in the song, which …

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Recommendations for starting hemodialysis in salicylate toxicity

June 30, 2015, 9:03 pm

Screen Shot 2015-06-30 at 5.55.50 PM★★★½☆

Extracorporeal Treatment for Salicylate Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup. Juurlink D et al. Ann Emerg Med 2015 May 8 [Epub ahead of print]

Abstract

Aspirin is an especially dangerous poison for a number reasons:

  • • It’s easy to purchase over-the-counter in large quantities
  • • Even after a life-threatening acute ingestion of salicylate, a patient can present

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Tox Tunes #97: Resurrection Mary (Ian Hunter)

June 21, 2015, 9:38 am

Combining Chicago lore, poisons, and a ghost, this is the perfect “Tox Tune” to post the weekend before smaccUS descends on the Windy City.

“Resurrection Mary,” which appeared on Ian Hunter’s 1996 album The Artful Dodger, recounts the famous Chicago ghost story involving about a vanishing hitchhiker who is periodically sited near the Resurrection Cemetery in southwest …

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Looking back: the first FOAMed meeting in the U.S.

June 20, 2015, 1:29 pm

FOAM mtg 2010

This photograph, from November 2010, documents what was to my knowledge the first #FOAMed get-together on U.S. soil. Gathered that evening at a tapas restaurant in San Francisco during the “Essentials of EM” conference were (from left to right):

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Illustrated case report of phenol exposure

June 18, 2015, 4:03 pm

Phenol

Phenol

★★★½☆

Phenol Toxicity Following Cutaneous Exposure to Creolin®:A Case Report. Vearrier D et al. J Med Toxicol 2015 Jun;11:227-231.

Abstract

This paper is worth looking at for the excellent color photographs of the partial thickness skin burns induced by exposure to Creolin®, which contains carbolic acid (phenol), sodium hydroxide, and isopropanol.

A 9-year-old girl was brought to the emergency department …

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