Having just returned from the American Institute of Ultrasound in Medicine meeting in San Diego, I have not yet had a chance to note that several days ago the eminent Egerton Y. Davis IV announced in the Welsh town of Llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogoch that UCEM is set to begin publication of “The Poison Preview”. This journal will be dedicated to the …
Hydroxocobalamin and Sodium Thiosulfate Versus Sodium Nitrite and Sodium Thiosulfate in the Treatment of Acute Cyanide Toxicity in a Swine (Sus Scrofa) Model. Bebarta VS et al. Ann Emerg Med April 2010;55:345-351.
When this article was posted online back in December, I reviewed it and gave it three-and-a-half skulls. Now that it is available in print, …
httpv://www.youtube.com/watch?v=DMzoqpyUbhg
The blues-rock band Canned Heat took their name from Tommy Johnson’s 1928 classic “Canned Heat Blues”. “Amphetamine Annie” — with its repeated admonition “speed kills” — was probably the best-known anti-drug song of the 1960s.
Dialysis in the poisoned patient. Bayliss G. Hemodialysis Int 2010 March 19 [Epub ahead of print]
This is a helpful revieew of enhanced elimination techniques available for the management of toxicology patients. Some key points emphasized in the article:
• Intermittent hemodialysis is ideal for low-molecular-weight, water-soluble toxins with small volumes of distribution and minimal binding to proteins …
Severe metabolic acidosis secondary to coadministration creatine and metformin, a case report. Saidi H, Mani M. Am J Emerg Med (2010) 28:388.e5-e6
This case report from Tehran describes a 42-year-old body builder who developed anion-gap metabolic acidosis (pH 7.25, anion gap 22 mEq/L) after taking a combination of metformin and creatine for 3 weeks. He presented with anuria …
BMJ online has a nice brief case report and review of life-threatening metformin-induced lactic acidosis (MALA). Some key points:
• Although deliberate acute metformin overdose generally has a good prognosis, inadvertent chronic metformin toxicity is extremely serious and still has a mortality rate of about 50%.
• Precisely identifying the diagnosis and be difficult early on, since alternative considerations such as …
In a must-read post on the British Medical Journal (BMJ) blog site, Richard Smith argues that the traditional peer-review system as a means to filter medical literature before publication is “slow, expensive, largely a lottery, poor at detecting errors and fraud, anti-innovatory, biased, and prone to abuse”. He suggests moving from a model of “filter, then publish” to one of …
httpv://www.youtube.com/watch?v=EJ7o34UZyXQ
Tommy Johnson — along with Son House and Charley Patton — was one of the key figures in the development of early Delta blues. According to Robert Palmer’s indispensable book Deep Blues, Johnson . . .
The Guardian (U.K.) today has a piece “In Focus: Mephedrone” in which they talk to four people: a user, a mother, a dealer, and a doctor. Unfortunately, despite its title, the piece is so unfocused that I really didn’t learn anything from it. Who exactly are these people. Is “Jack Starks” — the user — his real name? …
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