Archive for April 2010

Pediatric Nicotine Ingestions

April 30, 2010, 9:24 pm

★★★★☆

Unintentional Child Poisonings Through Ingestion of Conventional and Novel Tobacco Products.  Connolly GN et al.   Pediatrics 2010;125:896-899.

Full Text

This study looked retrospectively at all cases of children < 6 years of age ingesting only tobacco products that were reported to 61 regional poison control centers in the years 2006-2008.  A total of 13,705 cases were identified, 70% of…

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Amiodarone neurotoxicity

April 27, 2010, 10:38 pm

★★★½☆

Hepatic Dysfunction and Neurotoxicity in a Patient Receiving Long-Term Low-Dose Amiodarone Therapy.   Arkun A et al. J Emerg Med 2010;38:337-339.

Abstract

This instructive case report describes a 90-year-old male who developed neurotoxicity 18 months after starting amiodarone 200 mg daily for paroxysmal atrial fibrillation.  Neurologic manifestations included confusion, dizziness, proximal lower extremity weakness, and ataxia.  Work-up revealed mild…

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Cognitive Bias and Premature Closure

April 26, 2010, 2:42 pm

Life in the Fast Lane discusses an interesting case that demonstrates the danger of premature closure (that is, jumping to conclusions) when evaluating complex acutely ill patients.  We had an example of this pitfall — fortunately avoided by the sharp emergency doc — presented at tox rounds this morning.  A sixty-year-old man was brought into the emergency department…

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Tox Tunes #17: When I Get Low I Get High (Ella Fitzgerald)

April 25, 2010, 3:31 pm

The “First Lady of Song” — Ella Fitzgerald (1917-1996) — would have been 93 years old today. Her collection Ella Fitzgerald Sings the Gershwin Songbook has TPR’s vote as one of the two greatest albums in the history of American music (the other vote goes to The Complete Recordings of Robert Johnson). Happy Birthday, Ella!

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Mephedrone after the ban

April 25, 2010, 2:46 pm

The Telegraph (U.K.) published a long piece this week surveying the use of mephedrone in Britain now that the Home Secretary has classified the drug as a class-B substance.  In the article, Dr. Paul Dargan, a toxicologist at Guy’s and St. Thomas’ hospitals, talks about the effects of mephedrone:

“‘The pattern of toxicity is very similar…

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