Cyanide Poisoning and Cardiac Disorders: 161 Cases. Fortin JL et al. J Emerg Med May 2010;38:467-476,
This manufacturer-sponsored, multicenter retrospective study reviewed cases of patients with smoke inhalation or cyanide ingestion who received early hydroxocobalamin in the field, before arriving at hospital. The study period was from January 1995 to July 2008. The authors paid special attention to the …
httpv://www.youtube.com/watch?v=ZMQ9tLBxx6U
Am in New York after having a great time visiting Wentworth-Douglass Hospital in Dover, New Hampshire. Managed to catch the performance of “La Bayadere” at American Ballet Theatre last night. This was a double treat. The first was that the performance featured Diana Vishneva as Nikiya. Vishneva is one of the great ballerinas in dance, and has the most marvelously supple back on the planet. Second, “La Bayadere” has more toxicology . . .
Iatrogenic lipid emulsion overdose in a case of amlodipine poisoning. West PL et al. Clin Toxicol [Epub ahead of print]
This report describes a rare case of lipid emulsion overdose. A 71-year-old woman ingested 27 5-mg tablets of amlodipine and was treated with lipid emulsion therapy (LET) after developing hypotension resistant to fluid, pressors, and hyperinsulinemia-eugylcemia therapy. A …
Life in the Fast Lane — as part of their ongoing “Toxicology Conundrum” series — has posted an excellent review of the assessment and management of caustic ingestions. It is accompanied by a fascinating vintage advertisement for drain cleaner that presents a complex psychological and domestic tragedy in a single frame. A must-see!…
A Retrospective Review of Supratherapeutic Modafinil Exposures. Carstairs SD et al. J Med Toxicol [published online 01 April 2010]
Modafinil (Provigil) is a non-amphetamine stimulant that is sometimes used by college students as an aid to facilitate concentration and studying. This retrospective review examined all cases of supratherapeutic modafinil exposures reported to the California Poison Control System in the …
KXAN-TV in Austin, Texas had a story this week on the growing popularity of spice (also called K2) in their viewing area around the University of Texas. As we reported back in February, “spice” is a mixture of herbs and/or tobacco laced with synthetic cannabinoids . . .
Cerebral Vasculopathy After 4-Bromo-2,5-Dimethoxyphenethylamine Ingestion. Ambrose JB et al. The Neurologist May 2010;16:199-202.
4-bromo-2,5-dimethoxyphenethylamine (2C-B) is a psychedelic phenethylamine first synthesized in the 1970s and subsequently used as a replacement for — or addition to — “ecstasy” at rave events. It stimulates both the alpha-1 and serotonin 5-HT2 receptors, producing vasospasm and vivid visual hallucinations. Street names for 2C-B …
The World Health Organization this week posted a worldwide image library and database of venomous snakes and corresponding approved antivenoms. This is an invaluable resource. For example, if treating a patient bitten by his pet eyelash palm-pitviper (Bothriechis schlegelii), one can easily look up the appropriate antivenom: Polyvalent Antivenom ICP manufactured by the Instituto Clodomiro Picado in …
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