Archive for May 2010

Hand Sanitizers: A Risk for Children?

May 8, 2010, 1:02 pm

Pediatric Ingestions of Hand Sanitizers: Debunking the Myth.  Mrvos R, Krenzelok EP.  Pediatr Emerg Care Oct 2009;25:665-666.

Abstract

Since alcohol-based hand sanitizers are 124 proof (62% ethanol), they pose a potential threat to small children who may ingest the product.  To measure the gravity of this threat, the authors retrospectively reviewed exposures to these products in children less than 6 …

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Drug-Induced Metabolic Acidosis

May 7, 2010, 1:32 pm

★★★★☆

Pharmacologically-Induced Metabolic Acidosis.  Liamis G et al.  Drug Saf 2010 May 1; 33:371-391.

Abstract

This somewhat wordy article is a complete review of drug-induced metabolic acidosis, and well worth reading for those interested in expanding their knowledge beyond the mnemonic MUDPILES or reviewing the 4 types of renal tubular acidosis.  There is so much detail here that the paper is …

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Antidote Challenge

May 5, 2010, 1:50 pm

Life in the Fast Lane has posted a neat Antidote Challenge that’s a comprehensive review, ideal for medical students and residents preparing for board or in-service exams.…

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NRG-1? Buphedrone? Flephedrone? — What will follow meow-meow and where will it come from?

May 4, 2010, 11:57 am

I missed it when it was first published several weeks ago, but the Daily Mail (U.K.) has a must-read piece tracing the connection between drug-manufacturing laboratories in China and the marketing of new, untested, and potentially dangerous drugs.  Since mephedrone (meow-meow) was banned in Great Britain several weeks ago, there is intense speculation as to what its successor will be. …

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Tox Tunes #18: Day Tripper (The Beatles)

May 4, 2010, 1:21 am

“[Lennon] evidently felt sufficiently versed in the ‘counterculture’ associated with [LSD] to poke fun at those who took it without changing their outlook. The lyric of Day Tripper, he later explained, was an attack on ‘weekend hippies’ – those who donned floral shirts and headbands to listen to ‘acid rock’ between 9-to-5 office-jobs.”

Revolution in the Head: The Beatles’

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It ain’t tox, but . . .

May 2, 2010, 1:30 pm

Just listened to a superb lecture on “Dominating the Ventilator” in the emergency department  by Scott Weingart, posted on his website EMCrit Lectures.  It is based on the NIH’s ARDSnet protocol, and manages to make the whole topic logical and easy to follow.  Highly recommended.

By the way, both EMCrit Lectures and EMCrit Blog are available …

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Yohimbe and Priapism

May 1, 2010, 8:56 pm

★★½☆☆

Refractory Priapism Associated with Ingestion of Yohimbe Extract.  Myers A et al.  J Med Toxicol 2009;5:223-225.

Abstract

Yohimbine is an alkaloid found in the bark of the African evergreen tree Pausinystalia yohimbe (picture). An alpha-2 adrenergic antagonist, over-the-counter yohimbine is sometimes ingested as an aphrodisiac to enhance male erections.  Common adverse effects include gastrointestinal distress, hypertension, tachycardia, headache, and …

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