Archive for July 2010

Update on “legal” smoking highs

July 31, 2010, 1:20 pm

★★★½☆

Spice drugs as a new trend: Mode of action, identification and legislation. Vardakou I et al. Toxicol Lett 2010:197:157-162.

Abstract

Spice, like K2, is a mixture of herbs laced with various synthetic cannabinoids.  It is usually sold over the counter or via the internet, labelled as “incense” and “not for human consumption”.  Although it is not clear…

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Desmopressin and the “pis-quiz”: unexpected causes of low sodium

July 29, 2010, 9:06 pm

★★★☆☆

Two Unusual Pediatric Causes of Dilutional Hyponatremia. Boetzkes S et al.  Pediatr Emerg Med July 2010;26:503-505.

Abstract

Hyponatremia, especially if it is acute and develops rapidly, can be associated with significant and sometimes severe consequences: nausea, vomiting, headache, decreased mental status, seizures and coma.  Fatal cases have been reported. This paper, from Belgium, presents two cases of clinically severe…

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Medical examiner’s cause of death: is it reliable?

July 28, 2010, 10:28 pm

★★★½☆

Medical examiner and medical toxicologist agreement on cause of death. Manini AF et al. Forensic Sci Int (2010), doi:10.1016/j.forsciint.2010.06.021

Abstract

This is a somewhat interesting paper on a very important topic.  The authors, all from New York City, identified 256 fatalities over a 7-year period that were evaluated by the medical examiner’s office (MEO) and the local poison…

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Methemoglobinemia: mind the gap!

July 28, 2010, 12:42 am

★★½☆☆

Case Report: Is threshold for treatment of methemoglobinemia the same for all? A case report and literature review.  El-Husseini A, Azarov N.  Amer J Emerg Med 2010;28:748.e5-748.e10

Abstract

This puzzling and ultimately unsatisfying case report is redeemed by some spectacular clinical pictures illustrating the findings in methemoglobinemia.  A 78-year-old woman hospitalized for a CVA workup underwent transesophageal echocardiography, receiving…

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The straight dope about the urine toxicology screens

July 27, 2010, 12:39 am

Academic Life in Emergency Medicine has a very handy pocket card listing the causes of false positive results on the urine drug screen, and duration of positive tests after last drug use.  It is suitable for printing out and carrying around in a notebook.

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