The Poison Review

Clinical Effects and Lethal and Forensic Aspects of Propofol. Levy RJ J Forensic Sci 2010 Oct 15. doi: 10.1111/j.1556-4029.2010.01583.x. [Epub ahead of print]

Abstract

Since the death of Michael Jackson last year, the serious matter of propofol abuse has become a much-discussed issue.  This abuse is especially prevalent among medical professionals, who have access to this dangerous drug — a drug that is still not considered a controlled substance.  This article reviews the clinical indications, pharmacology, adverse effects, and abuse potential of drug, as well as published reports of propofol-related accidental deaths and suicides.  It also cites a recent report of homicide by propofol.

To read my column about propofol in Emergency Medicine News, clock here.