Comprehensive review of new designer drugs

March 15, 2012, 12:05 am

★★★½☆

Here Today, Gone Tomorrow  . . . and Back Again? A Review of Herbal Marijuana Alternatives (K2, Spice), Synthetic Cathinones (Bath Salts), Kratom, Salvia divinorum, Methoxetamine, and Piperazines. Rosenbaum CD et al.  J Med Toxicol 2012;8:15-32.

Abstract

This review of many new drugs of abuse is quite comprehensive (202 references!), and details what is known about the pharmacology, pharmacokinetics, clinical effects, laboratory detection and clinical management of each class of drugs discussed. A lot have this material has been covered before, but I was not very familiar with methoxetamine, a ketamine analog with effects similar to those of phencyclidine (PCP). There have been several recent articles about this drug — including some too recent to be included in this article’s reference list. I will review methoxetamine in detail tomorrow.

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The science of designer drugs; essential review

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