25I-NBOMe: a dangerous new hallucinogen

November 15, 2012, 4:33 pm

25I-NBOMe

★★★½☆

25C-NBOMe — New potent hallucinogenic substance identified on the drug market. Zuba D et al. Forensic Sci Int. 2012 Sep 15. pii: S0379-0738(12)00390-8. doi: 10.1016/j.forsciint.2012.08.027. [Epub ahead of print]

Abstract

The New Orleans Times-Picayune online reported earlier this month that an Arkansas man died at in October after taking a small amount of the hallucinogenic phenethylamine 25I-NBOMe (also called “N-bomb”) at a music festival. It is not clear from the article how the drug was specifically identified.

According to the report, 21-year-old Clayton Otwell of Little Rock had been drinking Red Bull and vodka at the Voodoo Fest when he was given a single drop of the drug applied to nasal mucosa:

Otwell immediately started babbling incoherently, [a friend] said. She got him to the medical tent at the festival, but within 30 minutes, he had a seizure and never regained consciousness.

25I-NBOMe is often sold on blotter paper as “artificial LSD” or “artificial mescaline”. It is an extremely potent serotonin agonist at the 5-HT2A receptor.

The Forensic Science International article specifically discusses chemical and analytical aspects of a related drug, 25C-NBOMe (aka Pandora, Dime, Vortex), but does touch on the entire class of 25-NBOMe (or NBOMe) psychedelics which, as the authors note, “have nearly no history of human use prior to 2010 when they first became available online”. Since there is not much else in the medical literature about these dangerous hallucinogens, the article is very much worth reading.

Erowid has posted a summary of fatalities related to 25I-NBOMe.

Related posts:

2C-I: designer hallucinogen linked to North Dakota deaths (read comment section)

 

 

4 Comments:

  1. Mike Says:

    The material in question was first synthesized by Heim as part of his dissertation back in 2003. I believe he did some post-doc work at Purdue, which continued to study this series of materials:
    http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000001221

  2. Leon Says:

    Mike:

    Thanks for pointing that out. Heim’s thesis is reference #4 in the Zuba et al paper.

  3. Mike Says:

    Frome @Erowid via twitter: Louisiana becomes second state to schedule 25I-NBOMe, following multiple deaths associated with it. http://t.co/fZkEXlLw

  4. Leon Says:

    Mike:

    Thanks for this update.