Archive for June 2014

Flagellate dermatitis — when the shiitake hits the fan

June 30, 2014, 1:41 pm

Flagellate dermatitis

Flagellate dermatitis


Shiitake dermatitis recorded by French Poison Control Centers — new case series with clinical observations. Boels D et al. Clin Toxicol 2014 Jul;52:625-628.


Just when you thought it was safe to go back to Whole Foods . . .

I must admit — I had not idea that eating raw shiitake mushrooms can cause a “very spectacular …

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Must-read: getting started in online emergency medicine education and FOAMed

June 28, 2014, 6:40 pm


Five Strategies to Effectively Use Online Resources in Emergency Medicine. Thoma B et al. Ann Emerg Med 2014 Jun 21 [Epub ahead of print]


FOAM (Free Open Access Meducation) was born, legend has it, in 2012 during an international conference in Dublin, as Dr. Mike Cadogan  stared into the dregs of a pint of …

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Does cannabis cause acute coronary syndromes?

June 24, 2014, 8:31 pm


Is recent cannabis use associated with acute coronary syndromes? An illustrative case series. Casier I et al. Acta Cardiol 2014 Apr;69:131-136.


Tetrahydrocannabinol (THC) has a number of well-documented effects on the cardiovascular system:

  • increased heart rate
  • increased blood pressure
  • decreased peripheral vascular resistance
  • orthostatic hypotension

THC may also be associated in rare cases with induction of ventricular arrhythmias. In …

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Overdose and death from pediatric chloral hydrate sedation

June 23, 2014, 7:06 pm

Chloral hydrate

Chloral hydrate


Pediatric Chloral Hydrate Poisonings and Death Following Outpatient Procedural Sedation. Nordt SP et al. J Med Toxicol 2014 Jun;10:219-222.


The medical use of chloral hydrate goes back to the 19th century. It is still used occasionally today for pediatric pre-procedural sedation. The risks inherent in this practice are illustrated in this excellent short article. The authors …

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An unusual complication of injecting paraffin oil to enhance body sculpting

June 20, 2014, 9:25 am


Severe hypercalcaemia, nephrocalcinosis, and multiple paraffinomas caused by paraffin oil injections in a young bodybuilder. Gyldenløve M et al. Lancet 2014 Jun14;383:2098


This short case report describes a 23-year-old male bodybuilder who presented with scrotal pain. The patient also admitted to shortness of breath and chest tightness. Workup for infection and nephrolithiasis was negative. Laboratory tests revealed anemia, renal …

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No, Craigslist is not a research tool

June 17, 2014, 8:22 pm

"wax" or "dab"

“wax” or “dab”


A new method of cannabis ingestion: The dangers of dabs? Loflin M, Earleywine M. Addict Behav 2014 May 28:39:1430-1433.


As TPR has reported before, “dab” (also called “butane hash oil” or “wax”) is a highly concentrated formulation of tehtrahydrocannabinol (THC) in a process using butane as a solvent. Whereas marijuana flowers can have a THC …

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Must-read: the approval of Zohydro, and more tox on the web

June 15, 2014, 10:56 pm


Must-read of the week: Stephen S. Hall’s article “How Much Does It Hurt?” in the current edition of  New York magazine gives the best explanation I’ve seen of how the Food and Drug Administration ended up approving the extended-release hydrocodone product ZohydroER, even though their scientific advisory committee recommended against approval by a vote of 11-2. According to …

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Review: marijuana and health

June 14, 2014, 2:19 pm


Adverse Health Effects of Marijuana Use. Volkow ND et al. N Engl J Med 2014 Jun 5;370:2219-2227.

No abstract available

This review article by Dr. Nora Volkow and her colleagues at the National Institute on Drug Abuse is in most respects a rather fair and balanced look at the potential adverse effects of marijuana use. Among the potential negative effects …

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Inter-species case series: seizures associated with a novel synthetic cannabinoid

June 9, 2014, 8:57 pm


‘Crazy Monkey’ Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid. Gugelmann H et al. Clin Toxicol 2014 Jun 6 [Epub ahead of print]


This amazing case report (or inter-species case series) comes from the California Poison Control System and UC-SF. A 22-year-old man brings his dog to the veterinarian because of possible …

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