TPR Podcast Episode #12: 25 years of weird and wacky toxicology papers

September 26, 2016, 9:54 am

25th Anniversary The Poison Review Podcast: Wild, Wacky and Weird Toxicology Articles From The Last Quarter-Century

“It is universally well known, that in ingesting our common food, there is created or produced in the bowels of human creatures, a great quantity of wind.”  Benjamin Franklin


Stool osmolar gap = 290 – 2*(stool Na + stool K)   [normal 50-100 mOsm/kg]

If stool osmolar gap < 50, diarrhea is secretory

If stool osmolar gap > 100, diarrhea is osmotic

Osmotic diarrhea will resolve with fasting; secretory diarrhea will not

Here is a link to a stool osmolar gap calculator


To read WebMD’s discussion of cases similar to that of the airline stewardess,

click here.


NOTE: As indicated above, current thinking is that a normal stool osmolar gap is

between 50 and 100 mOsm/kg. Interestingly, by that measure the stool

osmolar gap in this case of the air stewardess with puzzling diarrhea was

actually normal.


Other items discussed on the podcast:


Hennig Brand

Golden Fountain: The Complete Guide to Urine Therapy (book)

Your Own Perfect Medicine (book)


To read my “Toxicology Rounds” column on autourotherapy, click here



Quizzler (Podcast #11): In James Joyce’s novel Ulysses, Leopold Bloom’s father had committed suicide by self-poisoning. The Quizzler: what agent did Rudolph Bloom (né Rudolph Virág) use to kill himself? The answer: aconite. The winner, Dr. Richard Hamilton of Philadelphia, received a TPR t-shirt. Congratulations to Dr. Hamilton!


This episode’s Quizzler is at the end of the podcast. The winner will receive a $10 Amazon gift certificate as well as the TPR t-shirt. Our rules have changed slightly. Rather than awarding the prize to the first correct answer, we will take all correct answers submitted before the deadline and randomly select a winner. The deadline for submission is October 11, 2016, 6 pm (Chicago time.) Send submissions to: Good luck!


Dr. Steve Aks with a Lava light

Dr. Steve Aks with a Lava light


Dr. Tim Erickson threatening to try autourotherapy

Dr. Tim Erickson threatening to try autourotherapy


Drs. Tim Erickson, Steve Aks, and Leon Gussow

Drs. Tim Erickson, Steve Aks, and Leon Gussow


The Poison Review newsletter, 1998

The Poison Review newsletter, 1998






  1. Rich Hamilton Says:

    Well done lads from a big fan! 25 years of toxic teaching that I have greatly enjoyed.
    PS Good luck in your new venture Tim!

  2. Leon Gussow Says:


    Thank you for your support over the years!