Archive for March 2017

TPR Podcast Episode #14: VX and the Assassination of Kim Jong-Nam

March 30, 2017, 2:43 pm

When Kim Jong Nam — the half-brother of Korean leader Kim Jong Un — was assassinated in February while waiting for a flight at the Kuala Lumpur International Airport in Malaysia, attention was focused on one of the deadliest chemicals in the world: the nerge agent VX. What is VX, why is it such an effective poison, and how are victims of exposure managed medically. These are some of the questions we'll be examining in this edition of the TPR podcast.

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Tox Tunes #109: I Killed Robert Johnson (The Stone Foxes)

March 5, 2017, 10:20 pm

More myths and legends are attached to the life of Robert Johnson (1911 – 1938) than surround any other American blues artist. It’s said that he sold his soul to the devil down at a Mississippi crossroads in return for the ability to play guitar with a technique that musicians like Eric Clapton are still trying to replicate. It’s said …

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Labetalol in acute cocaine toxicity: is it safe?

March 1, 2017, 2:10 pm


Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol. Richards JR et al. J Emerg Med 2017 Mar;52:311-313.


There has long been a debate among toxicologists — still unresolved — as to whether it is safe to use a beta-blocker to treat cocaine-related hypertension and tachycardia. The (theoretical) concern is that since cocaine is both an α- and …

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