Archive for May 2017

Lipid rescue therapy for local anesthetic toxicity: is less more

May 25, 2017, 5:09 pm


Adverse events associated with a large dose of intravenous lipid emulsion for suspected local anesthetic toxicity. Corwin DJ et al. Clin Toxicol 2017 Jul;55:603-7.


The key word in the title of this case report is “associated” — a.though the authors do not emphasize the point, it’s not at all clear that all of the adverse events described were actually …

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Hemodialysis and the intubated salicylate-toxic patient

May 20, 2017, 12:53 pm


The association of hemodialysis and survival in intubated salicylate-poisoned patients. McCabe DJ, Lu JJ. Am J Emerg Med 2017 Apr 10 [Epub ahead of print]


[Disclosure: the co-authors of this paper are members of the Toxikon Consortium in Chicago, as am I.]

This retrospective observational study looked at cases from the Illinois Poison Center over 12 years (2003 thru …

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Hemp seed oil may possibly (but not probably) cause cannabinoid poisoning

May 10, 2017, 1:41 am

hemp seed oil★★½☆☆

Cannabinoid Poisoning by Hemp Seed Oil in a Child. Chinello M et al. Pediatr Emerg Care 2017;33:344-345.


This interesting but non-dispositive short case report from Italy suggests that, in rare instances, commercially marketed hemp seed oil can cause mild cannabinoid toxicity. A 2-year-7-month old male was brought to hospital with altered mental status and several hours of “decreased alertness, …

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Tox Tunes #110: Nutmeg (John Legend & Stephen Colbert)

May 7, 2017, 1:38 pm

Started thinking about this song again earlier in the week as I prepared to take part in an hour-long discussion of the spice on Connecticut Public Radio’s Colin McEnroe Show. The discussion touched on many aspects the spice: historical, economic, culinary, medicinal, and toxicological.

To listen to the show, click here.

To read my 2011 Emergency Medicine News

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