Archive for February 2018

Flubromazolam: a potent designer benzodiazepine

February 27, 2018, 10:20 pm

Flubromazolam

★★★☆☆

Flubromazolam — A new life-threatening designer benzodiazepine. Lukasik-Glebocka M et al. Clin Toxicol 2016;54:66-68.

Abstract

Last month, the Peoria (IL) Journal-Star reported that local police had seized samples of two rarely seen designer sedatives: flubromazolam (alleged street name “liquid Xanax“) and etizolam.

This paper from Poland presents a case report of flubromazolam exposure. A 27-year-old male …

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Can we improve prognostic indications in acetaminophen-induced hepatic failure?

February 9, 2018, 4:13 pm

★★½☆☆

Hypoglycemia and lactic acidosis outperform King’s College criteria for predicting death or transplant in acetaminophen toxic patients. Levine M et al. Clin Toxicol 2018 Jan 5 [Epub ahead of print]

Abstract

The standard tool used in evaluating acetaminophen-poisoned patients for possible orthotopic liver transplantation (OLT) is the King’s College Criteria (KCC).

The KCC identify 2 groups of patients who …

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Can smoking marijuana cause meningitis?

February 2, 2018, 2:30 pm

Cryptococcus neoformans (wikipedia.org)

★★½☆☆

Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency. Shapiro BB et al. BMJ Case Rep 2018 Jan 26 [Epub ahead of print]

Abstract

Can smoking marijuana cause meningitis?

The question is not unreasonable. A wide range of pathogenic fungi — including Aspergillus and various Cryptococcus species — have been isolated from dispensary-grade medical marijuana …

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