Archive for the ‘Medical’ Category

Fatal caffeine overdose: useful paper despite BuzzFeed-worthy title

July 20, 2014, 3:56 pm

KFDA – NewsChannel 10 / Amarillo News, Weather, Sports

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Fatal Caffeine Intoxication: A Series of Eight Cases from 1999 to 2009. Banerjee P et al. J Forensic Sci 2014 May;59:865-868.

Abstract 

This article is classic example of scientific bait and switch, a deceptive tactic not dissimilar to the use of “click bait” by websites like BuzzFeed. The …

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Two cases of laboratory-confirmed exposure to 25B-NBOMe

July 18, 2014, 5:51 pm

25I-NBOMe blotter paper

25I-NBOMe blotter paper

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Two cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe. Tang MHY et al. Clin Toxicol 2014 Jun;52:561-565.

Abstract

The NBOMe series of drugs are substituted phenethylamines. They act as agonists at both the 5-HT2A receptors and the α-receptors. Because of these actions, they can cause both hallucinations …

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Case report: guanfacine overdose

July 17, 2014, 7:52 pm

Intuniv (Guanfacine)

Intuniv (Guanfacine)

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Prolonged Bradycardia and Hypotension Following Guanfacine Extended Release Overdose. Walton J et al. J Child Adolesc Psychopharmacol 2014 Jul 10 [Epub ahead of print]

Reference 

Guanfacine is a central α2-agonist with a mechanism of action similar to that of clonidine. Originally marketed as an antihypertensive agent, it is now available as an extended-release preparation (Imtuniv) …

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Review of cannabinoid hyperemesis syndrome

July 16, 2014, 9:41 pm

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A hot mess: A case of hyperemesis. Cheung E et al.  Can Fam Physician 2014 Jul;60:633-637.

Full Text

With medical marijuana now legal in 23 states plus the District of Columbia, and recreational marijuana legal in 2 states, it is essential that all emergency and primary care physicians become familiar with the adverse effects that can ensue from regular use …

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Tox Tunes #84: Pass the Dutchie (Musical Youth)

July 13, 2014, 5:50 pm

The term “dutchie” now refers to a marijuana product, possibly a “blunt” made from a cigar such as a Dutch Masters. But it probably didn’t in 1982 when the British reggae band Musical Youth released this hit. The song is a cover of the Mighty Diamonds’ “Pass the Koutchie” — a “koutchie” being a pipe …

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Acute respiratory distress syndrome following intralipid emulsion therapy

July 12, 2014, 6:24 pm

intralipid★★½☆☆

Acute respiratory distress syndrome following verapamil overdose treated with intravenous lipid emulsion; A rare life-threatening complication. Martin C et al.  Ann Fr Anesth Reanim 2014 [Epub ahead of print]

Reference

This interesting French case report is a textbook example of how not to use intralipid emulsion therapy (ILE) in calcium-channel-block (CCB) overdose.

It describes a 51-year-old woman who present to …

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Mussel Beach: Paralytic Shellfish Poisoning

July 11, 2014, 6:06 pm

mussels-pot-1024x683★★★☆☆

Paralytic Shellfish Poisoning: A Case Series. Hurley W et al. West J Emerg Med 2014 Jul;15:378-381.

Full Text

Paralytic shellfish poisoning (PSP)is caused by saxitoxin,  an alkaloid produced by certain marine dinoflagellates and released during algae blooms that produce a so-called “red tide.” (Actually, the water can be various colors, or even clear, during these blooms.) The …

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Retrospective review of nutmeg toxicity

July 9, 2014, 10:55 pm

nutmeg-profect1★★½☆☆

Nutmeg Poisonings: A Retrospective Review of 10 Years Experience from the Illinois Poison Center: 2001-2011. Ehrenpreis JE et al. J Med Toxicol 2014;10:148-151.

Abstract

Just when you thought it was safe to go back to the eggnog bowl . . .

Nutmeg is the seed of the aromatic evergreen Myristica fragrans. It contains a number of volatile oils, …

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Tox on the web: intranasal naloxone, chloral hydrate toxicity, and more!

July 6, 2014, 10:43 pm

 

Legalized recreational marijuana in Colorado – the first six months: NPR’s talk show On Point recently had an interesting discussion of Colorado’s experience with recreational marijuana. Guests included Alicia Caldwell, an editorial writer for the Denver Post, and Dr. Richard Zane, Chair of Emergency Medicine at the University of Colorado Medical Center. Dr. Zane pointed out that many …

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