Illustrated case report of phenol exposure

June 18, 2015, 4:03 pm




Phenol Toxicity Following Cutaneous Exposure to Creolin®:A Case Report. Vearrier D et al. J Med Toxicol 2015 Jun;11:227-231.


This paper is worth looking at for the excellent color photographs of the partial thickness skin burns induced by exposure to Creolin®, which contains carbolic acid (phenol), sodium hydroxide, and isopropanol.

A 9-year-old girl was brought to the emergency department …

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Case series: 11 hospital workers symptomatic after ingesting “synthetic marijuana” brownies

June 16, 2015, 2:56 pm


Cluster of Acute Toxicity from Ingestion of Synthetic Cannabinoid-Laced Brownies. Obafemi AI et al. J Med Toxicol 2015 May 13 [Epub ahead of print]


This case series describes 11 patients brought to hospital after inadvertently ingesting brownies laced with the synthetic cannabinoid AM-2201.

All 11 patients were hospital workers who ingested brownies brought to work by a staff …

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Podcast: Managing the crashing tox patient with ECMO

June 16, 2015, 12:08 am

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As I wrote about in a recent column for Emergency Medicine News, extracorporeal membrane oxygenation (ECMO) may be the next big thing in managing the severely ill, crashing overdose patient in whom usual therapy is not working. On the new podcast posted today at the EDECMO website, Steve Aks and I got together over Skype with Joe Bellezzo, Zack …

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Dramatic recent increase in cases and deaths associated with use of synthetic cannabinoids

June 13, 2015, 5:22 pm


Increase in Reported Adverse Health Effects Related to Synthetic Cannabinoid Use —United States, January-May 2015. MMWR 2015 Jun 12;64:618-619.

Full Text

I have to say that this report shocked me some. Although I was aware of an increased number of news reports of incidents related to synthetic cannabinoids, I really had no idea the increased number of cases involving …

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How lipid rescue therapy works: it’s more than just a sink

June 9, 2015, 7:37 pm


Multi-modal contributions to detoxification of acute pharmacotoxicity by a triglyceride micro-emulsion. Fettiplace MR et al. J Control Release 2015 Jan 28;198:62-70


This study, from Guy Weinberg’s lab at the University of Illinois, used a rat model of bupivacaine toxicity, along with and computational analysis, to investigate the mechanisms by which lipid rescue therapy (LRT) might act in treating overdose …

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“Rick and Jerry”: a salute

June 8, 2015, 6:26 pm

At the Emergency Physicians Monthly website, Mel Herbert posted a lovely tribute to Rick Bukata and Jerry Hoffman as they pass off the lead anchoring duties on Emergency Medicine Abstracts to a new generation of medical educators.

I think Mel’s piece captures the impact and influence of the Abstracts perfectly. When I started listening to the monthly tapes in the …

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Tox Tunes #96: Champagne and Reefer (Rolling Stones and Buddy Guy)

June 7, 2015, 11:47 pm

This is a great version of Muddy Waters’ song “Champagne and Reefer” by the Stones and Buddy Guy. Those who will be in Chicago for SMACCus may want to stop into Buddy Guy’s Legends, a club that is virtually downtown and where Buddy himself sometimes shows up to play.

Related post:

Tox Tunes #32: Champagne and Reefer (Muddy Waters)

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Episode #9: TPR Podcast on hemodialysis in poisonings

June 1, 2015, 5:05 pm

In this episode, the team discusses recommendations regarding initiation of hemodialysis from the Extracorporeal Treatments in Poisoning (ExTRIP Workgroup). Specific agents covered include methanol, lithium, acetaminophen, and theophylline. Also, we reveal the real identify of the Stay Puft Marshmallow Man from the movie Ghostbusters. To access the audio file, click on the title above and go to the end of the show notes. Better yet, sign up for a free subscription at the iTunes store.
Podcast Episode

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Tox Tunes #95: Dead Flowers (Townes Van Zandt)

May 31, 2015, 11:09 pm

The Rolling Stones’ original version of “Dead Flowers” was on their 1971 Sticky Fingers album, along with a number of other songs definitely or possibly about drugs, including “Brown Sugar,” “Moonlight Mile,” and “Sister Morphine.”

The song was written in the late 1960s, when Keith Richards was hanging out with the country-rock musician Gram Parsons. Although fans …

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